Non Invasive Prenatal Test (NIPT)
DESCRIPTION
NIPT is a DNA test on maternal blood to screen pregnancies for the most common fetal chromosome anomalies: trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). Also the gender of the fetus can be determined.
RELIABILITY
The reliability of NIPT is very high (more than 99% for Down syndrome).
SAMPLE
Specific test kits provided by GENDIA are required: 10 ml blood in specific blood tubes is required from the mother.
The samples have to be sent by Express mail to GENDIA’s lab in Antwerp (Belgium), and arrive there within 2 days of withdrawal.
INDICATIONS
Although NIPT can be performed in every pregnancy, it is especially indicated:
- If the triple test or first trimester screening indicates an increased risk for Down syndrome, trisomy 18 or trisomy 13
- Advanced maternal age
TIMING
From gestation week 11.
TURNAROUND TIME
Usually you (and your midwife or physician) receive the NIPT result through e-mail in 1 week.
CONTRAINDICATIONS
NIPT is not the test of choice when there is:
- Triplets
- Fetal anomalies on ultrasound
- Known genetic anomalies that cannot be diagnosed by NIPT
PRICE
日本のお客様のための情報
テストの要点を以下に要約します。:
- 説明:NIPTは、最も一般的な胎児異数性(染色体21,18,13)の妊娠をスクリーニングする母体血液に関するDNA検査である。 この試験は、胎児由来のDNAを含む母体の血液サンプルに対して行う。胎児の性別は、必要に応じて決定される。
- タイミング:妊娠10週目から、しかし11週目〜13週目に最適。
- ターンアラウンドタイム:<2週間
- 信頼性:ダウン症候群の感度と特異度はいずれも> 99%です。