STID is a Screening Test for Inherited Diseases for future parents. The test screens for the most common gene anomalies (409 mutations) in 105 of the most common genetic diseases with recessive inheritance. These include cystic fibrosis, spinal muscular atrophy, mental retardation, deafness, blindness, and many other serious genetic disorders affecting children, including Jewish disorders.
The overall frequency of such recessive diseases is 1%, which is higher than the frequency of Down syndrome.
If a healthy couple carries a mutation in the same gene they have a 25% risk that their offspring will be affected by a recessive disease.
In that case prenatal diagnosis with chorionic biopsy (CVS) or amniocentesis (AC) can be offered.
